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NRAS Antibody (N-term)

NRAS Antibody (N-term)

ArtNr	ABC-AP7745A
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton Flow Cytometry Western Blot Immunofluorescence Primary Antibodies small GTPases Ras Subfamily
Typ	Antibody Polyclonal
Applikationen	WB, FC, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Smalley,K.S., Cancer Res. 68 (14), 5743-5752 (2008) Banerji,U., Mol. Cancer Ther. 7 (4), 737-739 (2008)
NCBI	NP_002515.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GTPase NRas,Transforming protein N-Ras,NRAS,HRAS1
Similar products	NRAS, HRAS1, GTPase NRas, Transforming protein N-Ras
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Manufacturer - Category	Primary Antibodies; Cancer; Signal Transduction; B cell receptor signaling; T cell activation; T cell receptor signaling; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling
Manufacturer - Targets	This NRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human NRAS.
Bio Background	NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB14459
Gene Name	NRAS
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Predicted Reactivity	C, Pig
Calculated Molecular Weight	21229
Antigen Source	HUMAN
Antigen Region	72-101
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000 WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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