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NRAS Antibody (N-term)

NRAS Antibody (N-term)

Item no.	ABC-AP7745A
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton Flow Cytometry Western Blot Immunofluorescence Primary Antibodies small GTPases Ras Subfamily
Type	Antibody Polyclonal
Applications	WB, FC, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Smalley,K.S., Cancer Res. 68 (14), 5743-5752 (2008) Banerji,U., Mol. Cancer Ther. 7 (4), 737-739 (2008)
NCBI	NP_002515.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GTPase NRas,Transforming protein N-Ras,NRAS,HRAS1
Similar products	NRAS, HRAS1, GTPase NRas, Transforming protein N-Ras
Available
Manufacturer - Category	Primary Antibodies; Cancer; Signal Transduction; B cell receptor signaling; T cell activation; T cell receptor signaling; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling
Manufacturer - Targets	This NRAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human NRAS.
Bio Background	NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB14459
Gene Name	NRAS
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Predicted Reactivity	C, Pig
Calculated Molecular Weight	21229
Antigen Source	HUMAN
Antigen Region	72-101
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000 WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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