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AREG Antibody (C-term)

AREG Antibody (C-term)

Hersteller	Abcepta
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Menge	400 ul
Host	Rabbit
ArtNr	ABC-AP7776b
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Primary Accession	P15514
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This protein is associated with a psoriasis-like skin phenotype.
Bio References	Shim, J.Y., J. Korean Med. Sci. 23 (5), 857-863 (2008) Eckstein, N., J. Biol. Chem. 283 (2), 739-750 (2008) Revillion, F., Ann. Oncol. 19 (1), 73-80 (2008) Kimura, H., Nature 348 (6298), 257-260 (1990)
Clonality	Polyclonal
Clone/Animal Names	RB14426
Gene ID	374
Gene Name	AREG (HGNC:651)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	AREG Antibody (C-term) (Cat.#AP7776b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AREG antibody detected the AREG protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	AREG Antibody (C-term) (Cat. #AP7776b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AREG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_001648
Isotype	Rabbit Ig
Calculated MW	27895
Antigen Region	222-252
Antigen Source	HUMAN
Target/Specificity	This AREG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human AREG.
NCBI Accession	NP_001648.1

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ABC-AP7776b-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 04.07.2024

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