ACE Antibody (C-term)

Synthetic Peptide

ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active.

Polyclonal

1636

Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of anti-ACE Antibody (C-term) (Cat.#AP7793b) in mouse lung tissue lysates (35ug/lane). ACE (arrow) was detected using the purified Pab.

1:1000

149715

HUMAN

NP_000780.1; NP_001171528.1; NP_690043.1