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MAP2K2 Antibody (S226)

MAP2K2 Antibody (S226)

ArtNr	ABC-AP7961f
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MAP2K2, MEK2, Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, MAPK/ERK kinase 2, MKK2, PRKMK2, MAP kinase kinase 2, MAPKK 2, MEK 2
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Primary Accession	P36507
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Bio References	Burroughs, K.D., et al., Mol. Cancer Res. 1(4):312-322 (2003). Tran, H., et al., Mol. Cell. Biol. 23(20):7177-7188 (2003). Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003). Li, Y., et al., J. Biol. Chem. 278(16):13663-13671 (2003). Liu, X., et al., J. Biol. Chem. 277(42):39312-39319 (2002).
Clonality	Polyclonal
Clone/Animal Names	RB12777
Gene ID	5605
Gene Name	MAP2K2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-MAP2K2-pS226. ctrl at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: MOLT-4 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 44 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P36506; Q63932; Q90891; Q05116; Q01986; P29678; P31938; Q02750; Q63980; Q10664; Q24324
Predicted	D, E, Ha, M, Rb, Rat, X, C
Isotype	Rabbit Ig
Calculated MW	44424
Antigen Region	204-233
Antigen Source	HUMAN
Target/Specificity	This MAP2K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from human MAP2K2.
NCBI Accession	NP_109587.1

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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