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MAP2K2 Antibody (S226)

MAP2K2 Antibody (S226)

Item no.	ABC-AP7961f
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MAP2K2, MEK2, Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, MAPK/ERK kinase 2, MKK2, PRKMK2, MAP kinase kinase 2, MAPKK 2, MEK 2
Available
Primary Accession	P36507
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Bio References	Burroughs, K.D., et al., Mol. Cancer Res. 1(4):312-322 (2003). Tran, H., et al., Mol. Cell. Biol. 23(20):7177-7188 (2003). Li, S.P., et al., Cancer Res. 63(13):3473-3477 (2003). Li, Y., et al., J. Biol. Chem. 278(16):13663-13671 (2003). Liu, X., et al., J. Biol. Chem. 277(42):39312-39319 (2002).
Clonality	Polyclonal
Clone/Animal Names	RB12777
Gene ID	5605
Gene Name	MAP2K2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-MAP2K2-pS226. ctrl at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: MOLT-4 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 44 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P36506; Q63932; Q90891; Q05116; Q01986; P29678; P31938; Q02750; Q63980; Q10664; Q24324
Predicted	D, E, Ha, M, Rb, Rat, X, C
Isotype	Rabbit Ig
Calculated MW	44424
Antigen Region	204-233
Antigen Source	HUMAN
Target/Specificity	This MAP2K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-233 amino acids from human MAP2K2.
NCBI Accession	NP_109587.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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