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CSF3R Antibody (Center)

CSF3R Antibody (Center)

ArtNr	ABC-AP9075C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	G-CSF-R, CSF3R, GCSFR, CD114, Granulocyte colony-stimulating factor receptor, G-CSF receptor
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Primary Accession	Q99062
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	CSF3R is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble.
Bio References	Yerges, L.M., et.al., J. Bone Miner. Res. 24 (12), 2039-2049 (2009) Germeshausen, M., et.al., Blood 114 (16), 3504-3505 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB23568
Gene ID	1441
Gene Name	CSF3R
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-CSF3R Antibody (Center) at 1:1000 dilution Lane 1: Caco2 whole cell lysate Lane 2: KG-1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 92 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human colon carcinoma reacted with CSF3R Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	CSF3R Antibody (Center) (Cat.#AP9075c) FC analysis of ZR-75-1 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	92156
Antigen Region	252-280
Antigen Source	HUMAN
Target/Specificity	This CSF3R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the Central region of human CSF3R.
NCBI Accession	NP_000751.1; NP_724781.1; NP_758519.1

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ABC-AP9075C-datasheet.pdf

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Menge: 400 ul

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