IL-21 Antibody

ArtNr	ABC-ASC10142
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Primary
Applikationen	WB, ICC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Parrish-Novak J, Dillon SR, Nelson A, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000; 408:57-63. Ozaki K, Kikly K, Michalovich D, et al. Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain. Proc. Natl. Acad. Sci. USA. 2000; 97:11439-44. Asao H, Okuyama C, Kumaki S, et al. The common γ-chain is an indispensable subunit of the IL-21 receptor complex. J. Immunol. 2001; 167:1-5.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IL-21 Antibody: Za11,IL-21,Interleukin-21,Za11,interleukin 21
Similar products	IL-21, Za11, Interleukin-21, interleukin 21, IL-21 Antibody: Za11
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Manufacturer - Applications	IL-21 antibody can be used for detection of IL-21 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2 µg/mL.
Manufacturer - Category	Primary Antibodies; Cancer; Immunology; Cytokine; Interleukin signaling; Jak-STAT signaling KEGG
Manufacturer - Targets	IL21; At least two isoforms of IL-21 are known to exist; this antibody will detect both isoforms. IL-21 antibody is predicted to not cross-react with other members of the interleukin protein family.
Storage Conditions	IL-21 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	IL-21 Antibody: A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Clonality	Polyclonal
Gene Name	IL21
Reactivity	H
Calculated Molecular Weight	18653
Antigen Source	Homo sapiens
Purification	IL-21 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	IL-21 antibody can be used for detection of IL-21 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2 µg/mL.
Positive Control	HL60 Cell Lysate; THP-1 Cell Lysate
Buffer	IL-21 Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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