Comparison

IL-21 Antibody

Item no. ABC-ASC10142
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ICC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Parrish-Novak J, Dillon SR, Nelson A, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 2000; 408:57-63.
Ozaki K, Kikly K, Michalovich D, et al.  Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain. Proc. Natl. Acad. Sci. USA. 2000; 97:11439-44.
Asao H, Okuyama C, Kumaki S, et al. The common γ-chain is an indispensable subunit of the IL-21 receptor complex. J. Immunol. 2001; 167:1-5.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias IL-21 Antibody: Za11,IL-21,Interleukin-21,Za11,interleukin 21
Similar products IL-21, Za11, Interleukin-21, interleukin 21, IL-21 Antibody: Za11
Available
Manufacturer - Applications
IL-21 antibody can be used for detection of IL-21 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2 µg/mL.
Manufacturer - Category
Primary Antibodies; Cancer; Immunology; Cytokine; Interleukin signaling; Jak-STAT signaling KEGG
Manufacturer - Targets
IL21; At least two isoforms of IL-21 are known to exist; this antibody will detect both isoforms. IL-21 antibody is predicted to not cross-react with other members of the interleukin protein family.
Storage Conditions
IL-21 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background
IL-21 Antibody: A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Clonality
Polyclonal
Gene Name
IL21
Reactivity
H
Calculated Molecular Weight
18653
Antigen Source
Homo sapiens
Purification
IL-21 Antibody is affinity chromatography purified via peptide column.
Antibody Form
Liquid
Application Notes
IL-21 antibody can be used for detection of IL-21 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2 µg/mL.
Positive Control
HL60 Cell Lysate; THP-1 Cell Lysate
Buffer
IL-21 Antibody is supplied in PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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