CD81 Antibody

ArtNr	ABC-ASC10915
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Oren R, Takahashi S, Doss C, et al. TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins. Mol. Cell Biol. 1990; 10:4007-15. Charrin S, le Naour F, Silvie O, et al. Lateral organization of membrane proteins: tetraspanins spin their web. Biochem. J. 2009; 420:133-54. Mannion BA, Berditchevski F, Kraeft SK, et al. Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29). J. Immunol. 1996; 157:2039-47. Tacvhibana I and Hemler ME. Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance. J. Cell Biol. 1999; 146:893-90.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Manufacturer - Category	Primary Antibodies; Immunology; Microbiology; Viral entry into host cell; Host-virus interaction; B cell receptor signaling; SARS-Human interaction partners
Manufacturer - Targets	CD81;
Storage Conditions	CD81 antibody can be stored at 4? for three months and -20?, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Bio Background	CD81 Antibody: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.
Clonality	Polyclonal
Gene Name	CD81 {ECO:0000303\|PubMed:8766544, ECO:0000312\|HGNC:HGNC:1701}
Reactivity	H, M, Rat
Calculated Molecular Weight	25809
Antigen Source	Homo sapiens
Purification	CD81 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	CD81 antibody can be used for detection of CD81 by Western blot at 2.5 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Positive Control	;
Buffer	CD81 Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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