CD81 Antibody

CD81;

CD81 Antibody: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.

CD81 {ECO:0000303|PubMed:8766544, ECO:0000312|HGNC:HGNC:1701}

25809

CD81 Antibody is affinity chromatography purified via peptide column.

CD81 antibody can be used for detection of CD81 by Western blot at 2.5 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.

CD81 Antibody is supplied in PBS containing 0.02% sodium azide.