AMIGO1 Antibody

ArtNr	ABC-ASC11725
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neural Adhesion Molecules Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	Kuja-Panula J, Kiiltomaki M, Yamashiro T, et al. AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. J. Cell Biol. 2003; 160:963-73. Chen Y, Hor HH, and Tang BL. AMIGO is expressed in multiple brain cell types and may regulate dendritic growth and neuronal survival. J. Cell Physiol. 2012; 227:2217-29.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
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Manufacturer - Category	Primary Antibodies; Neuroscience
Manufacturer - Targets	AMIGO1; AMIGO1 antibody is human, mouse, and rat reactive. AMIGO1 antibody is predicted to not cross-react with AMIGO2 or AMIGO3.
Storage Conditions	AMIGO1 antibody can be stored at 4? for three months and -20?, stable for up to one year.
Bio Background	The amphoterin-induced gene and ORF (AMIGO1) protein is a brain-enriched, glycosylated transmembrane immunoglobulin (Ig) superfamily protein with six extracellular leucine-rich repeats (LRRs) and one Ig-like domain. It and the related proteins AMIGO2 and AMIGO3 are thought to be cell adhesion molecules expressed on fiber tracts of neuronal tissues and participate in their formation (1). AMIGO1 has also been suggested to play important roles in dendritic outgrowth during development and could modulate the survival of developing and adult neurons (2).
Clonality	Polyclonal
Gene Name	AMIGO1
Reactivity	H, M, Rat
Calculated Molecular Weight	55239
Antigen Source	homo sapiens
Purification	AMIGO1 antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	AMIGO1 antibody can be used for detection of AMIGO1 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Positive Control	HeLa Cell Lysate
Buffer	AMIGO1 antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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