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BIRC5 Antibody (monoclonal) (M01)

ArtNr ABC-AT1299a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF, IP, ELISA
Clon 5B10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Citations 1.Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis.Horowitz JC, Ajayi IO, Kulasekaran P, Rogers DS, White JB, Townsend SK, White ES, Nho RS, Higgins PD, Huang SK, Sisson TH.Int J Biochem Cell Biol. 2011 Oct 25.2.The Closely Related RNA helicases, UAP56 and URH49, Preferentially Form Distinct mRNA Export Machineries and Coordinately Regulate Mitotic Progression.Yamazaki T, Fujiwara N, Yukinaga H, Ebisuya M, Shiki T, Kurihara T, Kioka N, Kambe T, Nagao M, Nishida E, Masuda S.Mol Biol Cell. 2010 Aug 15;21(16):2953-65. Epub 2010 Jun 23.
NCBI NP_001012270.1,NP_001012271.1,NP_001159.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Baculoviral IAP repeat-containing protein 5,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,BIRC5,API4,IAP4
Similar products BIRC5, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, API4, IAP4
Lieferbar
Manufacturer - Targets
BIRC5 (NP_001159, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Clonality
Monoclonal
Gene Name
BIRC5
Subtitle
Mouse monoclonal antibody raised against a partial recombinant BIRC5.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration
0.38mg/ml; 0.5mg/ml
Dilution
IF
IP
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
Org Accession
NP_001159
Gene Description
baculoviral IAP repeat-containing 5
Gene Summary
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene' s expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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