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BLR1 Antibody (monoclonal) (M01)

BLR1 Antibody (monoclonal) (M01)

ArtNr	ABC-AT1301a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neuroinflammation Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Clon	2C1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.PI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cells. El Haibi CP, et al. Mol Cancer, 2010 Apr 22. PMID 20412587.Serum BLC/CXCL13 concentrations and renal expression of CXCL13/CXCR5 in patients with systemic lupus erythematosus and lupus nephritis. Lee HT, et al. J Rheumatol, 2010 Jan. PMID 19955043.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines. Singh S, et al. Int J Cancer, 2009 Nov 15. PMID 19610059.
NCBI	NP_001707.1,NP_116743.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	C-X-C chemokine receptor type 5,CXC-R5,CXCR-5,Burkitt lymphoma receptor 1,Monocyte-derived receptor 15,MDR-15,CD185,CXCR5,BLR1,MDR15
Similar products	CXCR5, BLR1, MDR15, C-X-C chemokine receptor type 5, Burkitt lymphoma receptor 1, Monocyte-derived receptor 15, CD185, CXC-R5, CXCR-5, MDR-15
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Manufacturer - Targets	CXCR5 (NP_001707, 1 a.a. ~ 56 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.
Clonality	Monoclonal
Gene Name	CXCR5
Subtitle	Mouse monoclonal antibody raised against a partial recombinant CXCR5.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 E
Org Accession	NP_001707
Gene Description	chemokine (C-X-C motif) receptor 5
Gene Summary	This gene was identified as a gene specifically expressed in Burkitt' s lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist. [provided by RefSeq
Antigen Type	Recombinant Protein

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ABC-AT1301a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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