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CA8 Antibody (monoclonal) (M01)

ArtNr ABC-AT1359a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ELISA
Clon 1F7
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG3 Kappa
Citations CA8 mutations cause a novel syndrome characterized by ataxia and mild mental retardation with predisposition to quadrupedal gait. T?rkmen S, et al. PLoS Genet, 2009 May. PMID 19461874.Crystal structure of human carbonic anhydrase-related protein VIII reveals the basis for catalytic silencing. Picaud SS, et al. Proteins, 2009 Aug 1. PMID 19360879.Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis. Mori S, et al. J Bone Miner Metab, 2009. PMID 19172221.Carbonic anhydrase-related protein VIII promotes colon cancer cell growth. Nishikata M, et al. Mol Carcinog, 2007 Mar. PMID 17219437.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.
NCBI NP_004047.3
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Carbonic anhydrase-related protein,CARP,Carbonic anhydrase VIII,CA-VIII,CA8,CALS
Similar products CA8, CARP, CA-VIII, CALS, Carbonic anhydrase VIII, Carbonic anhydrase-related protein
Lieferbar
Manufacturer - Targets
CA8 (NP_004047, 40 a.a. ~ 139 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
Clonality
Monoclonal
Gene Name
CA8
Subtitle
Mouse monoclonal antibody raised against a partial recombinant CA8.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
WB: 1:500~1000
E
Org Accession
NP_004047
Gene Description
carbonic anhydrase VIII
Gene Summary
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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