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GSR Antibody (monoclonal) (M01)

GSR Antibody (monoclonal) (M01)

ArtNr	ABC-AT2273a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Clon	6B4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. Wang Y, et al. J Hum Genet, 2010 Aug. PMID 20485444.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. Moyer AM, et al. Cancer Epidemiol Biomarkers Prev, 2010 Mar. PMID 20200426.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
NCBI	NP_000628.2,NP_001182031.1,NP_001182032.1,NP_001182033.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Glutathione reductase,mitochondrial,GR,GRase,GSR,GLUR,GRD1
Similar products	GR, GSR, mitochondrial, GLUR, GRD1, Glutathione reductase, GRase
Lieferbar
Manufacturer - Targets	GSR (NP_000628, 413 a.a. ~ 522 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Clonality	Monoclonal
Gene Name	GSR
Subtitle	Mouse monoclonal antibody raised against a partial recombinant GSR.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 IHC
Org Accession	NP_000628
Gene Description	glutathione reductase
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT2273a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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