PAX2 Antibody (monoclonal) (M02)

ArtNr	ABC-AT3189a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Antibodies Western Blot Primary Antibodies By Organ Renal Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Clon	20000
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.c-Jun is essential for the induction of Il-1?] gene expression in in vitro activated Bergmann glial cells.Albanito L, Reddy CE, Musti AM.Glia. 2011 Sep 21. doi: 10.1002/glia.21244.2.The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.Doberstein K, Pfeilschifter J, Gutwein P.Carcinogenesis. 2011 Sep 16.
NCBI	NP_000269.2,NP_003978.2,NP_003979.2,NP_003980.2,NP_003981.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Paired box protein Pax-2,PAX2
Similar products	PAX2, Paired box protein Pax-2
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Manufacturer - Targets	PAX2 (NP_000269, 194 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
Clonality	Monoclonal
Gene Name	PAX2
Subtitle	Mouse monoclonal antibody raised against a partial recombinant PAX2.
Reactivity	H, Rat
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000
Org Accession	NP_000269
Gene Description	paired box 2
Gene Summary	PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Antigen Type	Recombinant Protein

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