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PAX2 Antibody (monoclonal) (M02)

PAX2 Antibody (monoclonal) (M02)

Item no.	ABC-AT3189a
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Antibodies Western Blot Primary Antibodies By Organ Renal Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	WB
Clone	20000
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.c-Jun is essential for the induction of Il-1?] gene expression in in vitro activated Bergmann glial cells.Albanito L, Reddy CE, Musti AM.Glia. 2011 Sep 21. doi: 10.1002/glia.21244.2.The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma.Doberstein K, Pfeilschifter J, Gutwein P.Carcinogenesis. 2011 Sep 16.
NCBI	NP_000269.2,NP_003978.2,NP_003979.2,NP_003980.2,NP_003981.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Paired box protein Pax-2,PAX2
Similar products	PAX2, Paired box protein Pax-2
Available
Manufacturer - Targets	PAX2 (NP_000269, 194 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
Clonality	Monoclonal
Gene Name	PAX2
Subtitle	Mouse monoclonal antibody raised against a partial recombinant PAX2.
Reactivity	H, Rat
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000
Org Accession	NP_000269
Gene Description	paired box 2
Gene Summary	PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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