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PRPF19 Antibody (monoclonal) (M07)

PRPF19 Antibody (monoclonal) (M07)

Hersteller	Abcepta
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Specific against	other
Clon	200000
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB, IF
Menge	100 ug
Host	Mouse
ArtNr	ABC-AT3441a
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Primary Accession	Q9UMS4
Antigen Type	Recombinant Protein
Application	WB, IF
Bio Background	PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al., 2008 [PubMed 18263876]).
Bio References	Regulation of Metnase's TIR binding activity by its binding partner, Pso4. Beck BD, et al. Arch Biochem Biophys, 2010 Jun 15. PMID 20416268.Molecular architecture of the human Prp19/CDC5L complex. Grote M, et al. Mol Cell Biol, 2010 May. PMID 20176811.Blom7alpha is a novel heterogeneous nuclear ribonucleoprotein K homology domain protein involved in pre-mRNA splicing that interacts with SNEVPrp19-Pso4. Grillari J, et al. J Biol Chem, 2009 Oct 16. PMID 19641227.Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair. Beck BD, et al. J Biol Chem, 2008 Apr 4. PMID 18263876.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.
Clonality	Monoclonal
Gene ID	27339
Gene Name	PRPF19 (HGNC:17896)
Subtitle	Mouse monoclonal antibody raised against a partial recombinant PRPF19.
Reactivity	H, M, Rat
Legend image 1	Immunofluorescence of monoclonal antibody to PRPF19 on HeLa cell . [antibody concentration 10 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	PRPF19 monoclonal antibody (M07), clone 2E5. Western Blot analysis of PRPF19 expression in PC-12((Cat # AT3441a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	PRPF19 monoclonal antibody (M07), clone 2E5. Western Blot analysis of PRPF19 expression in Hela S3 NE ( (Cat # AT3441a )
Type image 4	WB
Dilution image 4	1:500~1000
Legend image 5	PRPF19 monoclonal antibody (M07), clone 2E5. Western Blot analysis of PRPF19 expression in NIH/3T3((Cat # AT3441a )
Type image 5	WB
Dilution image 5	1:500~1000
Legend image 6	Western Blot analysis of PRPF19 expression in transfected 293T cell line by PRPF19 monoclonal antibody (M07), clone 2E5. Lane 1: PRPF19 transfected lysate(55.2 KDa). Lane 2: Non-transfected lysate.
Type image 6	WB
Dilution image 6	1:500~1000
Legend image 7	Detection limit for recombinant GST tagged PRPF19 is 0.3 ng/ml as a capture antibody.
Type image 7	E
Other Accession	NM_014502
Isotype	IgG2a Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	PRPF19 (NP_055317, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_055317.1
	Clone: 200000
Org Accession	NP_055317
Gene Description	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
Gene Summary	PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al., 2008 [PubMed 18263876]).[supplied by OMIM

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT3441a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 04.07.2024

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