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SERPINE1 Antibody (monoclonal) (M01)

ArtNr ABC-AT3824a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IP, ELISA
Clon 3F2
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Citations 1.Extracellular Matrix Remodeling by Bone Marrow Fibroblast-like Cells Correlates with Disease Progression in Multiple Myeloma.Slany A, Haudek-Prinz V, Meshcheryakova A, Bileck A, Lamm W, Zielinski C, Gerner C, Drach JJ Proteome Res. 2013 Dec 2.
NCBI NP_000593.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Plasminogen activator inhibitor 1,PAI,PAI-1,Endothelial plasminogen activator inhibitor,Serpin E1,SERPINE1,PAI1,PLANH1
Similar products SERPINE1, PAI-1, PAI1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1, PAI
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Manufacturer - Targets
SERPINE1 (NP_000593, 86 a.a. ~ 185 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Gene Name
SERPINE1
Subtitle
Mouse monoclonal antibody raised against a partial recombinant SERPINE1.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
IP
WB: 1:500~1000
WB: 1:500~1000
E
Org Accession
NP_000593
Gene Description
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Gene Summary
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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