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SERPINE1 Antibody (monoclonal) (M01)

SERPINE1 Antibody (monoclonal) (M01)

Item no.	ABC-AT3824a
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Cell Biology Cell Status Immunoprecipitation Western Blot ELISA Senescence Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IP, ELISA
Clone	3F2
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.Extracellular Matrix Remodeling by Bone Marrow Fibroblast-like Cells Correlates with Disease Progression in Multiple Myeloma.Slany A, Haudek-Prinz V, Meshcheryakova A, Bileck A, Lamm W, Zielinski C, Gerner C, Drach JJ Proteome Res. 2013 Dec 2.
NCBI	NP_000593.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Plasminogen activator inhibitor 1,PAI,PAI-1,Endothelial plasminogen activator inhibitor,Serpin E1,SERPINE1,PAI1,PLANH1
Similar products	SERPINE1, PAI-1, PAI1, PLANH1, Plasminogen activator inhibitor 1, Endothelial plasminogen activator inhibitor, Serpin E1, PAI
Available
Manufacturer - Targets	SERPINE1 (NP_000593, 86 a.a. ~ 185 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	SERPINE1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SERPINE1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IP WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_000593
Gene Description	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Gene Summary	This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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