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SLC25A13 Antibody (monoclonal) (M01)

ArtNr ABC-AT3911a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF, ELISA
Clon 4F4
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Citations Polymorphic variants of genes related to arginine metabolism and the risk of orofacial clefts. Hozyasz KK, et al. Arch Oral Biol, 2010 Aug 23. PMID 20739017.Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) in three Malay children. Ngu HL, et al. Malays J Pathol, 2010 Jun. PMID 20614727.Most common SLC25A13 mutation in 400 Chinese infants with intrahepatic cholestasis. Fu HY, et al. World J Gastroenterol, 2010 May 14. PMID 20458766.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.[Studies on the clinical manifestation and SLC25A13 gene mutation of Chinese patients with neonatal intrahepatic cholestasis caused by citrin deficiency] Xing YZ, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2010 Apr. PMID 20376801.
NCBI NP_001153682.1,NP_055066.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Calcium-binding mitochondrial carrier protein Aralar2,Citrin,Mitochondrial aspartate glutamate carrier 2,Solute carrier family 25 member 13,SLC25A13,ARALAR2
Similar products SLC25A13, ARALAR2, Citrin, Mitochondrial aspartate glutamate carrier 2, Solute carrier family 25 member 13, Calcium-binding mitochondrial carrier protein Aralar2
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Manufacturer - Targets
SLC25A13 (NP_055066, 2 a.a. ~ 80 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Gene Name
SLC25A13
Subtitle
Mouse monoclonal antibody raised against a partial recombinant SLC25A13.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
IF
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
Org Accession
NP_055066
Gene Description
solute carrier family 25, member 13 (citrin)
Gene Summary
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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