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SLC25A13 Antibody (monoclonal) (M01)

SLC25A13 Antibody (monoclonal) (M01)

Item no.	ABC-AT3911a
Manufacturer	Abcepta
Amount	100 ug
Category	Neuroscience Neuroinflammation Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Aging & Neurological Disorders Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, ELISA
Clone	4F4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Polymorphic variants of genes related to arginine metabolism and the risk of orofacial clefts. Hozyasz KK, et al. Arch Oral Biol, 2010 Aug 23. PMID 20739017.Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) in three Malay children. Ngu HL, et al. Malays J Pathol, 2010 Jun. PMID 20614727.Most common SLC25A13 mutation in 400 Chinese infants with intrahepatic cholestasis. Fu HY, et al. World J Gastroenterol, 2010 May 14. PMID 20458766.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.[Studies on the clinical manifestation and SLC25A13 gene mutation of Chinese patients with neonatal intrahepatic cholestasis caused by citrin deficiency] Xing YZ, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2010 Apr. PMID 20376801.
NCBI	NP_001153682.1,NP_055066.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Calcium-binding mitochondrial carrier protein Aralar2,Citrin,Mitochondrial aspartate glutamate carrier 2,Solute carrier family 25 member 13,SLC25A13,ARALAR2
Similar products	SLC25A13, ARALAR2, Citrin, Mitochondrial aspartate glutamate carrier 2, Solute carrier family 25 member 13, Calcium-binding mitochondrial carrier protein Aralar2
Available
Manufacturer - Targets	SLC25A13 (NP_055066, 2 a.a. ~ 80 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	SLC25A13
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SLC25A13.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000
Org Accession	NP_055066
Gene Description	solute carrier family 25, member 13 (citrin)
Gene Summary	This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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