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SLC2A4 Antibody (monoclonal) (M08)

ArtNr ABC-AT3919a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB
Clon 2D6
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b Kappa
Citations Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Case-control analysis of SNPs in GLUT4, RBP4 and STRA6: association of SNPs in STRA6 with type 2 diabetes in a South Indian population. Nair AK, et al. PLoS One, 2010 Jul 6. PMID 20625434.Measuring GLUT4 translocation in mature muscle fibers. Lauritzen HP, et al. Am J Physiol Endocrinol Metab, 2010 Aug. PMID 20501875.Regulation of cardiomyocyte Glut4 expression by ZAC1. Czubryt MP, et al. J Biol Chem, 2010 May 28. PMID 20363751.Long-term ethanol exposure inhibits glucose transporter 4 expression via an AMPK-dependent pathway in adipocytes. Feng L, et al. Acta Pharmacol Sin, 2010 Mar. PMID 20173759.
NCBI NP_001033.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Solute carrier family 2,facilitated glucose transporter member 4,Glucose transporter type 4,insulin-responsive,GLUT-4,SLC2A4,GLUT4
Similar products GLUT4, SLC2A4, Solute carrier family 2, facilitated glucose transporter member 4, Glucose transporter type 4, insulin-responsive, GLUT-4
Lieferbar
Manufacturer - Targets
SLC2A4 (NP_001033, 467 a.a. ~ 509 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
Clonality
Monoclonal
Gene Name
SLC2A4
Subtitle
Mouse monoclonal antibody raised against a partial recombinant SLC2A4.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
WB: 1:500~1000
Org Accession
NP_001033
Gene Description
solute carrier family 2 (facilitated glucose transporter), member 4
Gene Summary
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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