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SLC2A4 Antibody (monoclonal) (M08)

SLC2A4 Antibody (monoclonal) (M08)

Item no.	ABC-AT3919a
Manufacturer	Abcepta
Amount	100 ug
Category	Metabolism Glucose Homeostasis Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB
Clone	2D6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Case-control analysis of SNPs in GLUT4, RBP4 and STRA6: association of SNPs in STRA6 with type 2 diabetes in a South Indian population. Nair AK, et al. PLoS One, 2010 Jul 6. PMID 20625434.Measuring GLUT4 translocation in mature muscle fibers. Lauritzen HP, et al. Am J Physiol Endocrinol Metab, 2010 Aug. PMID 20501875.Regulation of cardiomyocyte Glut4 expression by ZAC1. Czubryt MP, et al. J Biol Chem, 2010 May 28. PMID 20363751.Long-term ethanol exposure inhibits glucose transporter 4 expression via an AMPK-dependent pathway in adipocytes. Feng L, et al. Acta Pharmacol Sin, 2010 Mar. PMID 20173759.
NCBI	NP_001033.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Solute carrier family 2,facilitated glucose transporter member 4,Glucose transporter type 4,insulin-responsive,GLUT-4,SLC2A4,GLUT4
Similar products	GLUT4, SLC2A4, Solute carrier family 2, facilitated glucose transporter member 4, Glucose transporter type 4, insulin-responsive, GLUT-4
Available
Manufacturer - Targets	SLC2A4 (NP_001033, 467 a.a. ~ 509 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
Clonality	Monoclonal
Gene Name	SLC2A4
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SLC2A4.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000
Org Accession	NP_001033
Gene Description	solute carrier family 2 (facilitated glucose transporter), member 4
Gene Summary	This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/1/2026

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