PINK1 Antibody

ArtNr	ABC-AW5456-U100
Hersteller	Abcepta
Menge	100 ul
Kategorie	Neuroscience Neuroinflammation Neural Mitochondrial Function Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
Citations	Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells. Maj MC, et al. Biochem Biophys Res Commun, 2010 Aug 27. PMID 20637729. Assessing the prevalence of PINK1 genetic variants in South African patients diagnosed with early- and late-onset Parkinson's disease. Keyser RJ, et al. Biochem Biophys Res Commun, 2010 Jul 16. PMID 20558144. Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit. Eggers C, et al. Neurology, 2010 Jun 1. PMID 20513816. Structural imaging in the presymptomatic stage of genetically determined parkinsonism. Reetz K, et al. Neurobiol Dis, 2010 Sep. PMID 20483373. Clinical and demographic characteristics of PINK1 mutation carriers--a meta-analysis. Kasten M, et al. Mov Disord, 2010 May 15. PMID 20461815.
NCBI	NP_115785.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase PINK1,mitochondrial,BRPK,PTEN-induced putative kinase protein 1,PINK1
Similar products	PINK1, mitochondrial, Serine/threonine-protein kinase PINK1, BRPK, PTEN-induced putative kinase protein 1
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Autophagy; Mitochondrion; Mitochondrion outer membrane
Manufacturer - Targets	Recombinant PINK1 protein was used to produced this monoclonal antibody.
Bio Background	This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease.
Clonality	Monoclonal
Gene Name	PINK1
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H, M, Rat
Calculated Molecular Weight	62769
Antigen Source	HUMAN
Antigen Region	Unknown
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	IF: 1:25 WB: 1:1000 IHC-P: 1:25 IHC-P: 1:25 IHC-P: 1:25
Antigen Type	Recombinant Protein

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Menge: 100 ul

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