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TMED10 Antibody (C-term)

TMED10 Antibody (C-term)

Hersteller	Abcepta
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Specific against	other
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Menge	100 ul
Host	Rabbit
ArtNr	ABC-AW5552-U100
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Primary Accession	P49755
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Bio References	Wang, H., et al. Mol. Biol. Cell 21(8):1398-1408(2010) Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) : Pardossi-Piquard, R., et al. J. Biol. Chem. 284(42):28634-28641(2009) Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) : Liu, S., et al. Eur. J. Neurosci. 28(10):1980-1988(2008)
Clonality	Polyclonal
Gene ID	10972
Gene Name	TMED10 (HGNC:16998)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	All lanes : Anti-TMED10 Antibody (C-term) at 1:1000 dilution Lane 1: PC-12 whole cell lysate Lane 2: NCI-H460 whole cell lysate Lane 3: Hela whole cell lysate Lane 4: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	All lanes : Anti-TMED10 Antibody (C-term) at 1:1000 dilution Lane 1: NIH/3T3 whole cell lysate Lane 2: PC-12 whole cell lysate Lane 3: NCI-H460 whole cell lysate Lane 4: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	All lanes : Anti-TMED10 Antibody (C-term) at 1:2000 dilution Lane 1: human pancreas lysate Lane 2: Hela whole cell lysate Lane 3: NCI-H460 whole cell lysate Lane 4: Neuro-2a whole cell lysate Lane 5: NIH/3T3 whole cell lysate Lane 5: PC-12 whole cell lysate Lane 5: U-87 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 3	WB
Dilution image 3	1:2000
Isotype	Rabbit Ig
Calculated MW	24976
Antigen Region	156-185
Antigen Source	HUMAN
Target/Specificity	This TMED10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human TMED10.

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Menge: 100 ul

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Lieferung vsl. bis 04.07.2024

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