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TMED10 Antibody (C-term)

TMED10 Antibody (C-term)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Amount	100 ul
Host	Rabbit
Item no.	ABC-AW5552-U100
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	P49755
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Bio References	Wang, H., et al. Mol. Biol. Cell 21(8):1398-1408(2010) Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) : Pardossi-Piquard, R., et al. J. Biol. Chem. 284(42):28634-28641(2009) Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) : Liu, S., et al. Eur. J. Neurosci. 28(10):1980-1988(2008)
Clonality	Polyclonal
Gene ID	10972
Gene Name	TMED10 (HGNC:16998)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	All lanes : Anti-TMED10 Antibody (C-term) at 1:1000 dilution Lane 1: PC-12 whole cell lysate Lane 2: NCI-H460 whole cell lysate Lane 3: Hela whole cell lysate Lane 4: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	All lanes : Anti-TMED10 Antibody (C-term) at 1:1000 dilution Lane 1: NIH/3T3 whole cell lysate Lane 2: PC-12 whole cell lysate Lane 3: NCI-H460 whole cell lysate Lane 4: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	All lanes : Anti-TMED10 Antibody (C-term) at 1:2000 dilution Lane 1: human pancreas lysate Lane 2: Hela whole cell lysate Lane 3: NCI-H460 whole cell lysate Lane 4: Neuro-2a whole cell lysate Lane 5: NIH/3T3 whole cell lysate Lane 5: PC-12 whole cell lysate Lane 5: U-87 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 3	WB
Dilution image 3	1:2000
Isotype	Rabbit Ig
Calculated MW	24976
Antigen Region	156-185
Antigen Source	HUMAN
Target/Specificity	This TMED10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human TMED10.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 7/4/2024