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Anti-TRPV4 (extracellular)-FITC

Anti-TRPV4 (extracellular)-FITC

ArtNr	ALO-ACC-124-F-10x50ul
Hersteller	Alomone
Menge	10 x 50 ul
Quantity options	10 x 50 ul 15 ul 2 x 50 ul 50 ul 5 x 50 ul
Kategorie	Metabolism Diabetes Glucose Homeostasis Antibodies Obesity Flow Cytometry Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	FC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	FITC
Purity	Affinity purified on immobilized antigen.
Formula	PBS pH7.4, 1% BSA with 0.05% sodium azide
Sequence	(C)EDQSN(S)TVPSYPA(S)RD, corresponding to amino acid residues 647-662 of rat TRPV4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Specificity	Polyclonal
Manufacturer - Type	Antibodies
Manufacturer - Applications	FC, LCI
Manufacturer - Category	Antibodies
Manufacturer - Targets	OTRPC4, VRL-2, VR-OAC, TRP12, Osm-9-Like TRP Channel 4
Manufacturer - Conjugate / Tag	Fluorescein isothiocyanate (FITC)
Country of Origin	Israel
Shipping Temperature	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Storage Conditions	Storage before Reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C - Storage after Reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Manufacturer - Format	Lyophilized powder
Short description	A Rabbit Polyclonal Antibody to TRPV4 Conjugated to the Fluorescent Dye FITC
Description	OTRPC4, VRL-2, VR-OAC, TRP12, Osm-9-Like TRP Channel 4 - A Rabbit Polyclonal Antibody to TRPV4 Conjugated to the Fluorescent Dye FITC
Clonality	Polyclonal
Homology	Rat - 14/16 amino acid residues identical; mouse - 13/16 amino acid residues identical; human - 12/16 amino acid residues identical
Standard quality control of each lot	Western blot analysis (unlabeled antibody, #ACC-124), and direct flow cytometry (labeled antibody).
Peptide confirmation	Confirmed by amino acid analysis and mass spectrometry
Reconstitution	15 µl or 50 µl double distilled water (DDW), depending on the sample size.
Antibody Concentration After Reconstitution	1 mg/ml
Preservative	1% BSA, 0.05% NaN3
Immunogen Location	3rd extracellular loop
Specificity	TRPV4
Immunogen source species	Rat
PH	7, 4
UNSPSC	41116161
Antigen Preadsorption Control	1 µg peptide per 1 µg antibody
Scientific Background	TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells1. According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three extra subfamilies are considered to belong to the TRP family; the TRPA, TRPML, and TRPP)1-4. The TRPV subfamily consists of six members, TRPV1-65.TRPV4 (also named OTRPC4) is activated under hypotonic conditions and serves as an osmoreceptor. TRPV4 is expressed in brain, liver, kidney, heart, testis and salivary gland6.

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ALO-ACC-124-F-10x50ul-safety-datasheet.pdf