Vergleich

Interleukin-8 (IL-8)

Hersteller Anogen
Kategorie
Typ Antibody Polyclonal
Specific against Human
Format Purified
Applikationen WB, ELISA, NT
Menge 1.0mg
Host Chicken
ArtNr ANOG-AI60001
Targets CXCL8
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
Chicken anti-human Interleukin-8 polyclonal antibody (IgY fraction).
Target Protein
Human IL-8
Immunogen
Highly purified recombinant human IL-8
Specificity
This antibody recognizes human Interleukin-8 (IL-8)
Purification
Protein G affinity purified
Species Reactivity
Human, others not tested
Cross Reactivity
This polyclonal antibody exhibits no detectable cross-reactivity with human serum albumin, bovine serum albumin, and other cytokines tested such as IL-1beta, IL-16, TNF-alpha, GM-CSF, MCSF, bFGF and MIP-1alpha.
Background
Interleukin 8 (IL-8), like IL-6, is secreted by macrophages and a variety of cells that express Toll-like receptors in response to the stimulation of pathogens. IL-8's primary function is to recruit neutrophils and other target cells through chemotaxis to the infected site to eliminate pathogens. IL-8 causes increased intracellular Ca2+, release of reactive oxygen species, and other physiological changes required for migration and phagocytosis. IL-8 is also known to promote angiogenesis.
Formulation
Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00mg/mL
Application info
ELISA: The antibody when used at 2.6ng/mL can detect recombinant human IL-8 coated on ELISA plate.Neutralization: Total chicken IgY fraction at the concentration of 50 ug/mL showed 60% inhibition of 10ng/mL IL-8 induced IL8RB/293 cell migration
Western Blot: The antibody, when used at concentration of 0.26 ug/mL will allow visualization of recombinant human IL-8.
Research Area
Cytokine, interleukin and chemotaxis
Storage
Store at -20C

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1.0mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 13.05.2024 

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