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KV4.3, Voltage Gated Potassium Channel

KV4.3, Voltage Gated Potassium Channel

Hersteller	Anogen
Kategorie	Antibodies Western Blot ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Typ	Antibody Polyclonal
Specific against	Mouse
Format	Purified
Applikationen	WB, ELISA
Protein Familie	Signal Transduction
Menge	0.1mg
Host	Rabbit
ArtNr	ANOG-AI80010A-0.1mg
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Description	Rabbit anti-mouse voltage-gated potassium channel (Kv) 4.3 polyclonal antibody
Target Protein	Voltage-gated potassium channel Kv4.3
Immunogen	A synthetic peptide (RTTLERYPDT) corresponding to amino acid 55-64 of mouse voltage-gated potassium channel Kv4.3, conjugated with KLH for immunization.
Specificity	This antibody is reactive to the 74kDa mouse Kv4.3 in mouse brain tissue extract on Western blot.
Purification	Protein G affinity purified
Species Reactivity	Mouse and other species with consensus Kv4.3 sequence (RTTLERYPDT)
Background	Kv4.3 is a member of the voltage-gated potassium channel family. Kv4.3 forms complex with K channel interacting protein and regulates the transient potassium efflux and repolarization in cardiac myocytes. Kv4.3 is highly expressed in brain tissue. It is a member of the rapid inactivating A-type Kv channel subfamily and is encoded by KCND3 gene in human. There are two isoforms of this protein with different sizes resulted from alternative splicing.
Formulation	Lyophilized in pH 7.4, 0.01M PBS.
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: Dilute the antibody 1:500, 000 for detection of the peptide coated on ELISA plate. Western blot: Dilute approx. 1:5, 000 for Western blotting to detect the 74kDa mouse Kv4.3 in mouse brain tissue extract.
Research Area	Life science research, stem cell factor signalling, cancer research
Storage	Store at -20C

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Menge: 0.1mg

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Lieferung vsl. bis 17.06.2024

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