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KV4.3, Voltage Gated Potassium Channel

KV4.3, Voltage Gated Potassium Channel

Manufacturer	Anogen
Category	Antibodies Western Blot ELISA Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Type	Antibody Polyclonal
Specific against	Mouse
Format	Purified
Applications	WB, ELISA
Protein Family	Signal Transduction
Amount	0.1mg
Host	Rabbit
Item no.	ANOG-AI80010A-0.1mg
eClass 6.1	32160702
eClass 9.0	32160702
Available
Description	Rabbit anti-mouse voltage-gated potassium channel (Kv) 4.3 polyclonal antibody
Target Protein	Voltage-gated potassium channel Kv4.3
Immunogen	A synthetic peptide (RTTLERYPDT) corresponding to amino acid 55-64 of mouse voltage-gated potassium channel Kv4.3, conjugated with KLH for immunization.
Specificity	This antibody is reactive to the 74kDa mouse Kv4.3 in mouse brain tissue extract on Western blot.
Purification	Protein G affinity purified
Species Reactivity	Mouse and other species with consensus Kv4.3 sequence (RTTLERYPDT)
Background	Kv4.3 is a member of the voltage-gated potassium channel family. Kv4.3 forms complex with K channel interacting protein and regulates the transient potassium efflux and repolarization in cardiac myocytes. Kv4.3 is highly expressed in brain tissue. It is a member of the rapid inactivating A-type Kv channel subfamily and is encoded by KCND3 gene in human. There are two isoforms of this protein with different sizes resulted from alternative splicing.
Formulation	Lyophilized in pH 7.4, 0.01M PBS.
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: Dilute the antibody 1:500, 000 for detection of the peptide coated on ELISA plate. Western blot: Dilute approx. 1:5, 000 for Western blotting to detect the 74kDa mouse Kv4.3 in mouse brain tissue extract.
Research Area	Life science research, stem cell factor signalling, cancer research
Storage	Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1mg

available

Delivery expected until 6/17/2024