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H. pylori (HP) cytotoxin associated gene A protein (CagA)

H. pylori (HP) cytotoxin associated gene A protein (CagA)

ArtNr	ANOG-MO-I40020A
Hersteller	Anogen
Menge	0.5mg
Kategorie	Oncology Antibodies ELISA Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody Monoclonal
Format	Aff. Pur
Applikationen	ELISA
Clon	10 E 9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a kappa
Protein Familie	Antigens
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	HP
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Description	Mouse monoclonal antibody (mAb) against the H. pylori cytotoxin associated gene A protein (CagA)
Target Protein	H. pylori cytotoxin associated gene A protein (CagA)
Immunogen	A highly immunogenic 32kD CagA fragment, recombinant
Specificity	The mAb reacts with H. pylori CagA.
Purification	Protein G affinity purified
Species Reactivity	Human
Cross Reactivity	Cross-reaction with other proteins has not been identified.
Myeloma	Sp2/0-Ag14
Background	Helicobacter pylori (H. pylori), a spiral rod shaped gram-negative bacterium, is frequently found in the stomach. In infected populations, 10-20% may develop gastritis and gastric ulcer and 1-2% may develop cancer. The genome of H. pylori isolates from carriers with symptoms contains a 40kb pathogenicity island encoding H. pylori cytotoxin, cytotoxin associated gene A protein (CagA) and other virulence associated factors. CagA is used as a biomarker for virulent H. pylori strains.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution	Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: Clone 10E9 can be used as capture antibody in sandwich ELISA. Anti-CagA clone 10E9 coated wells detect recombinant CagA antigen in combination with HRP conjugated anti-CagA clone 5C6, clone 3C10 and clone 3C1. In addition, clone 10E9 selectively detected cell lysate of a CagA containing H. pylori strain when HRP conjugated anti-CagA clone 3C10 was used. Western Blot: This clone detects the 32 kD band corresponding to the molecular weight of the recombinant CagA antigen (Immunogen).
Research Area	Bacteriology
Storage	Store at -20C

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Menge: 0.5mg

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Lieferung vsl. bis 20.11.2025