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H. pylori (HP) cytotoxin associated gene A protein (CagA)

H. pylori (HP) cytotoxin associated gene A protein (CagA)

Item no.	ANOG-MO-I40020A
Manufacturer	Anogen
Amount	0.5mg
Category	Oncology Antibodies ELISA Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody Monoclonal
Format	Aff. Pur
Applications	ELISA
Clone	10 E 9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a kappa
Protein Family	Antigens
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	HP
Available
Description	Mouse monoclonal antibody (mAb) against the H. pylori cytotoxin associated gene A protein (CagA)
Target Protein	H. pylori cytotoxin associated gene A protein (CagA)
Immunogen	A highly immunogenic 32kD CagA fragment, recombinant
Specificity	The mAb reacts with H. pylori CagA.
Purification	Protein G affinity purified
Species Reactivity	Human
Cross Reactivity	Cross-reaction with other proteins has not been identified.
Myeloma	Sp2/0-Ag14
Background	Helicobacter pylori (H. pylori), a spiral rod shaped gram-negative bacterium, is frequently found in the stomach. In infected populations, 10-20% may develop gastritis and gastric ulcer and 1-2% may develop cancer. The genome of H. pylori isolates from carriers with symptoms contains a 40kb pathogenicity island encoding H. pylori cytotoxin, cytotoxin associated gene A protein (CagA) and other virulence associated factors. CagA is used as a biomarker for virulent H. pylori strains.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution	Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: Clone 10E9 can be used as capture antibody in sandwich ELISA. Anti-CagA clone 10E9 coated wells detect recombinant CagA antigen in combination with HRP conjugated anti-CagA clone 5C6, clone 3C10 and clone 3C1. In addition, clone 10E9 selectively detected cell lysate of a CagA containing H. pylori strain when HRP conjugated anti-CagA clone 3C10 was used. Western Blot: This clone detects the 32 kD band corresponding to the molecular weight of the recombinant CagA antigen (Immunogen).
Research Area	Bacteriology
Storage	Store at -20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.5mg

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Delivery expected until 11/20/2025

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