Anti-Flt3 Ligand Antibody

Rabbit polyclonal antibody to Flt3 Ligand / Flt3L.

Recombinant human Flt3-Ligand.

Supplied in Phosphate Buffered Saline.

This antibody recognises the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I transmembrane glycoprotein which regulates the proliferation of early haematopoietic cells.Flt3L exists in both a membrane-bound and proteolytically cleaved soluble isoform, both of which are biologically active, and initiates cell proliferation/ differentiation signalling in co-operation with other colony stimulating factors (CSFs) and interleukins, by binding to and activating the tyrosine kinase receptor Flt3 (FLT3R), expressed highly by hematopoietic progenitor cells and stem cells.