Anti-IL-10 Antibody

ArtNr	ANTI-A283937-100
Hersteller	Antibodies.com
Menge	100 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies Immunostaining Functional Assays
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB, ELISA, FA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Manufacturer - Targets	IL-10
Storage Conditions	Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description	Rabbit polyclonal antibody to IL-10.
Clonality	Polyclonal
Immunogen	Recombinant human IL-10.
Concentration	1 mg/ml after reconstitution.
Manufacturer - Formulation	Supplied in Phosphate Buffered Saline.
Recommended dilutions	ELISA: 0.5 µg/ml, Functional Assays: 4.0 - 6.0 µg/ml, WB: 0.1 - 0.2 µg/ml
Manufacturer - Specificity	This antibody recognises human IL-10 (Interleukin-10), an 18.5kDa immunosuppressive cytokine originally known as cytokine synthesis inhibiting factor (CSIF), which specifically regulates immune-mediated inflammation and shares high sequence homology with murine IL-10 and the viral protein BCRF1.IL-10, produced by macrophages, mast cells, T cells, activated B cells and keratinocytes, inhibits the secretion of a variety of pro-inflammatory cytokines including TNFalpha, IL-1, IL-2, IL-3 and IL-8 and is chemotactic for CD8+ T cells. The suppressive ability of IL-10 has become a focus area for the treatment of Crohn’s disease, but with conflicting results.
Reconstitution	Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.

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Menge: 100 ug

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 3 Tage sparen

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