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HSP90B Antibody (Ab-254)

HSP90B Antibody (Ab-254)

ArtNr	AP50002
Hersteller	Abcepta
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, IF, IHC
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	HSP90AB1, HSP90B, HSPC2, HSPCB, HSP 84, HSP84, Heat shock 84 kDa, Heat shock protein HSP 90-beta, HSP 90
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Primary Accession	P08238
Antigen Type	Synthetic Peptide
Application	WB, IF, IHC
Bio Background	Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Bio References	Rebbe N.F., et al.Gene 53:235-245(1987). Rebbe N.F., et al.J. Biol. Chem. 264:15006-15011(1989). Hoffmann T., et al.Gene 74:491-501(1988). Lu L., et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. Wiemann S., et al.Genome Res. 11:422-435(2001).
Clonality	Polyclonal
Gene ID	3326
Gene Name	HSP90AB1 (HGNC:5258)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	Immunofluorescence analysis of HeLa cells, treated with TNF-a (20nM, 15mins), using HSP90B (Ab-254) antibody .
Type image 1	IF
Dilution image 1	1:100
Legend image 2	Western blot analysis of lysates from Hela, A431 cell line (from left to right), using HSP90B Antibody (Ab-254) (B0013). B0013 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Western blot analysis of extracts from CoLo cells (Lane 1), HepG2 cells (Lane 2) and 293 cells (Lane 3), using HSP90B (Ab-254) Antibody. The lane on the left is treated with synthesized peptide.
Type image 3	WB
Dilution image 3	1:1000
Legend image 4	Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HSP90B (Ab-254) antibody .
Type image 4	IHC
Dilution image 4	1:50-1:100

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Menge: 100 ul

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