Comparison

HSP90B Antibody (Ab-254)

Item no. AP50002
Manufacturer Abcepta
Amount 100 ul
Category
Type Antibody Primary
Applications WB, IF, IHC
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products HSP90AB1, HSP90B, HSPC2, HSPCB, HSP 84, HSP84, Heat shock 84 kDa, Heat shock protein HSP 90-beta, HSP 90
Available
Primary Accession
P08238
Antigen Type
Synthetic Peptide
Application
WB, IF, IHC
Bio Background
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Bio References
Rebbe N.F., et al.Gene 53:235-245(1987).
Rebbe N.F., et al.J. Biol. Chem. 264:15006-15011(1989).
Hoffmann T., et al.Gene 74:491-501(1988).
Lu L., et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Wiemann S., et al.Genome Res. 11:422-435(2001).
Clonality
Polyclonal
Gene ID
3326
Gene Name
HSP90AB1 (HGNC:5258)
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M, Rat
Legend image 1
Immunofluorescence analysis of HeLa cells, treated with TNF-a (20nM, 15mins), using HSP90B (Ab-254) antibody .
Type image 1
IF
Dilution image 1
1:100
Legend image 2
Western blot analysis of lysates from Hela, A431 cell line (from left to right), using HSP90B Antibody (Ab-254) (B0013). B0013 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
Type image 2
WB
Dilution image 2
1:1000
Legend image 3
Western blot analysis of extracts from CoLo cells (Lane 1), HepG2 cells (Lane 2) and 293 cells (Lane 3), using HSP90B (Ab-254) Antibody. The lane on the left is treated with synthesized peptide.
Type image 3
WB
Dilution image 3
1:1000
Legend image 4
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HSP90B (Ab-254) antibody .
Type image 4
IHC
Dilution image 4
1:50-1:100

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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