CD5 (Mantle Cell Lymphoma Marker)(B-B8), CF640R conjugate, 0.1mg/mL

Primary

Antibodies

CF640R

Room temperature

67 kDa

This antibody recognizes a 67 kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

2 years

41116161

0.05% sodium azide (CAS 26628-22-8)

PBS, 0.1% BSA, 0.05% azide

T cells activated with PHA

For research use only (RUO)

58685

Plasma membrane

Leukemia/lymphoma

Flow (surface) (expected)|Functional studies (published for clone)|IF (expected)