Vergleich

Cdk2 / p34cdc2 Serine-Threonine Kinase(AN4.3), CF640R conjugate, 0.1mg/mL

ArtNr B-BNC402316-100
Hersteller Biotium
Menge 100 uL
Quantity options 100 uL 500 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Clon AN4.3
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Xenopus laevis
Host Mouse
Isotype IgG2a Kappa
Konjugat/Tag CF640R
Citations

Cell Cycle (2016) 15(23):3203-3209. (WB)

ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Cdc2 related protein kinase; CDC28; CDC2A; CDK1; CDK2; CDKN2; Cell devision kinase 2; Cell division protein kinase 2; cyclin dependent kinase 2 alpha; kinase Cdc2; MPF; p33 protein kinase
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary
Manufacturer - Applications
WB (published)
Manufacturer - Category
Antibodies
Manufacturer - Targets
Cdk2|p34cdc2 Serine-Threonine Kinase
Manufacturer - Conjugate / Tag
CF640R
Manufacturer - Host
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Shipping Temperature
Room temperature
Storage Conditions
Store at 2 to 8°C|Protect fluorescent conjugates from light
Molecular Weight
34 kDa
Description
In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclindependent kinase 2 (Cdk2), also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2-related cyclin dependent kinases have been identified. These include Cdk3, Cdk4, Cdk5, PCTAIRE-1, PCTAIRE-2, PCTAIRE-3, Cdk6 Cdk7, Cdk8 and KKIALRE. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product origin
Animal
Ingredient of biological origin
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Special handling for PI and label
Protect from light
Undated stability guarantee in PI
2 years
Stability at RT during shipping (protected from light)
Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity
41116161
UNSPSC Commodity Title
Primary and secondary antibodies for multiple methodology
immunostaining detection application
Classified or regulated chemicals
0.05% sodium azide (CAS 26628-22-8)
Concentration
0.1 mg/mL
Storage buffer
PBS, 0.1% BSA, 0.05% azide
Dated shelf life printed on label
Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)
Recombinant full-length human Cdk2 protein
Clonality
Monoclonal
Regulatory Status
For research use only (RUO)
Human Gene Symbol
CDK2
Unigene
19192
Positive Control
HeLa cells. HeLa whole cell lysate.
Antibody target cellular localization
Nucleus
Antibody application notes
Inhibits activation of p34cdc2 kinase by cyclins; Immunoprecipitation; Kinase Assay; Western blot; Flow cytometry: 1-2 ug/mL; Optimal dilution for a specific application should be determined.
Expected Antibody Applications
WB (published for clone)
Manufacturer - Antibody Reactivity
Cdk2|p34cdc2 Serine-Threonine Kinase

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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