Anti-E Cadherin Rabbit Monoclonal Antibody

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

97456 MW

WB 1:1000-5000
IHC 1:50-200
ICC/IF 1:50-200
FC 1:20

Cadherin-1

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Cadherins, Calcium Binding Proteins, Calcium Signaling, Cancer, Cell Adhesion, Cytoskeleton/ECM, Invasion/Microenvironment, Signal Transduction, Signaling Pathway

Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
(Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria.

Boster Bio Anti-E Cadherin Rabbit Monoclonal Antibody catalog # M00063-4. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

CDH1, Arc-1, CAD1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), Cadherin-1, calcium-dependent adhesion protein, epithelial, CAM 120/80, CD324 antigen, CD324, CDH1, CDHE, cell-CAM 120/80, Cell-CAM120/80, ECAD, ECadherin, E-Cadherin, Epithelial cadherin, LCAM, L-CAM, UVOE-Cadherin, Uvomorulin