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Anti-ApoM Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M02451-2
Hersteller Boster
Menge 100 ul/vial
Quantity options 100 ul/vial 30 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, IHC
Clon 23A72
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity <20 pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Major prion protein,PrP,ASCR,PrP27-30,PrP33-35C,CD230,PRNP,ALTPRP,PRIP,PRP
Lieferbar
Manufacturer - Category
Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
25 kDa
Calculated Molecular weight
27661 MW
Clonality
Monoclonal
Application Details
WB 1:500-2000
IHC 1:50-200
FC 1:60
Gene Name
APOM
Gene Full Name
Major prion protein
Immunogen
A synthesized peptide derived from human ApoM
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
0.5mg/ml
Manufacturer - Research Category
Hematopoietic Progenitors, Neurodegenerative Disease, Neurology Process, Neuroscience, Stem Cells, Surface Molecules
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Protein Function
May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu (2+) or ZN (2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
Subcellular Localization
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of CU (2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Description
Boster Bio Anti-ApoM Rabbit Monoclonal Antibody catalog # M02451-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human.
Tissue Specificity
Ubiquitous.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul/vial
Lieferbar: In stock
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