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Anti-Phospho-IKB alpha (S36) Rabbit Monoclonal Antibody

Anti-Phospho-IKB alpha (S36) Rabbit Monoclonal Antibody

ArtNr	BOS-P01139-1
Hersteller	Boster
Menge	100 ul/vial
Quantity options	100 ul/vial 30 ul
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Flow Cytometry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC
Clon	25N33
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	NF-kappa-B inhibitor alpha,I-kappa-B-alpha,IkB-alpha,IkappaBalpha,Major histocompatibility complex enhancer-binding protein MAD3,NFKBIA,IKBA,MAD3,NFKBI
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	39 kDa
Calculated Molecular weight	35609 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 FC 1:50
Gene Name	NFKBIA
Gene Full Name	NF-kappa-B inhibitor alpha
Immunogen	A synthesized peptide derived from human Phospho-IKB alpha (S36)
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Concentration	0.5mg/ml
Manufacturer - Research Category	Cancer, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, NFKB Pathway, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, TLR Signaling
Protein Function	Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Subcellular Localization	Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Description	Boster Bio Anti-Phospho-IKB alpha (S36) Rabbit Monoclonal Antibody catalog # P01139-1. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse.
Tissue Specificity	Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine and colon.
Phospho Site	S36

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-P01139-1-datasheet.pdf

BOS-P01139-1-safety-datasheet.pdf