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EPHB4 Antibody

ArtNr CSB-PA007732ESR2HU-50ul
Hersteller Cusabio
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen IHC, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ephb4 antibody,EPHB4_HUMAN antibody,Ephrin receptor EphB4 antibody,Ephrin type-B receptor 4 antibody,Hepatoma Transmembrane Kinase antibody,HTK antibody,MYK 1 antibody,MYK1 antibody,TYRO 11 antibody,TYRO11 antibody,Tyrosine-protein kinase receptor HTK antibody,Tyrosine-protein kinase TYRO11 antibody
Similar products EPHB4, Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11), HTK MYK1 TYRO11
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Manufacturer - Targets
EPHB4
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
Ephb4 antibody, EPHB4_HUMAN antibody, Ephrin receptor EphB4 antibody, Ephrin type-B receptor 4 antibody, Hepatoma Transmembrane Kinase antibody, HTK antibody, MYK 1 antibody, MYK1 antibody, TYRO 11 antibody, TYRO11 antibody, Tyrosine-protein kinase receptor HTK antibody, Tyrosine-protein kinase TYRO11 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Ephrin type-B receptor 4 protein (300-540AA)
Dilution
ELISA:1:2000-1:10000
IHC:1:20-1:200
Background
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purified
General Research Areas
Cardiovascular
Initial Research Areas
Cardiovascular
Antigen Species
Human
Antigen
Recombinant Human Ephrin type-B receptor 4 protein (300-540AA)
Clonality
Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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