ERLIN2 Antibody

ArtNr	CSB-PA007791ESR2HU-50ul
Hersteller	Cusabio
Menge	50 ul
Quantity options	100 ul 50 ul
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Antibodies By Cell Type Carcinoma Sarcoma Obesity Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C8orf2 antibody,Chromosome 8 open reading frame 2 antibody,Endoplasmic reticulum lipid raft associated protein 2 antibody,Endoplasmic reticulum lipid raft-associated protein 2 antibody,ER lipid raft associated 2 antibody,ERLIN 2 antibody,Erlin-2 antibody,ERLIN2 antibody,ERLN2_HUMAN antibody,HGNC:1356 antibody,MGC87072 antibody,NET32 antibody,SPFH 2 antibody,SPFH domain containing protein 2 antibody,SPFH domain family member 2 antibody,SPFH domain-containing protein 2 antibody,SPFH2 antibody,SPG18 antibody,Stomatin prohibitin flotillin HflC/K domain containing protein 2 antibody,Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 antibody
Similar products	ERLIN2, Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2), C8orf2 SPFH2
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Manufacturer - Targets	ERLIN2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	C8orf2 antibody, Chromosome 8 open reading frame 2 antibody, Endoplasmic reticulum lipid raft associated protein 2 antibody, Endoplasmic reticulum lipid raft-associated protein 2 antibody, ER lipid raft associated 2 antibody, ERLIN 2 antibody, Erlin-2 antibody, ERLIN2 antibody, ERLN2_HUMAN antibody, HGNC:1356 antibody, MGC87072 antibody, NET32 antibody, SPFH 2 antibody, SPFH domain containing protein 2 antibody, SPFH domain family member 2 antibody, SPFH domain-containing protein 2 antibody, SPFH2 antibody, SPG18 antibody, Stomatin prohibitin flotillin HflC/K domain containing protein 2 antibody, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Erlin-2 protein (212-339AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IHC:1:20-1:200
Background	Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Neuroscience
Initial Research Areas	Neuroscience
Antigen Species	Human
Antigen	Recombinant Human Erlin-2 protein (212-339AA)
Clonality	Polyclonal

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Lieferung vsl. bis 25.12.2025

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