GREM1 Antibody

Polyclonal Antibody

GREM1

BMP antagonist 1 antibody, Cell proliferation inducing gene 2 protein antibody, Cell proliferation-inducing gene 2 protein antibody, CKTSF1B1 antibody, colorectal adenoma and carcinoma 1 antibody, Cysteine knot superfamily 1 antibody, Cysteine knot superfamily 1, BMP antagonist 1 antibody, Cysteine knot superfamily BMP antagonist 1 antibody, DAN domain family member 2 antibody, DAND2 antibody, Down regulated in Mos-transformed cells protein antibody, Down-regulated in Mos-transformed cells protein antibody, DRM antibody, grem1 antibody, GREM1_HUMAN antibody, Gremlin 1 homolog, cysteine knot superfamily antibody, Gremlin 1 like protein antibody, Gremlin 1, cysteine knot superfamily, homolog antibody, GREMLIN antibody, Gremlin-1 antibody, Gremlin1 antibody, IHG-2 antibody, IHG2 antibody, Increased in high glucose 2 antibody, Increased in high glucose protein 2 antibody, PIG2 antibody, Proliferation inducing gene 2 antibody, proliferation inducing gene 2 protein antibody

Recombinant Human Gremlin-1 protein (18-184AA)

Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2, inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).

>95%, Protein G purified

Signal Transduction

Recombinant Human Gremlin-1 protein (18-184AA)