IST1 Antibody

ArtNr	CSB-PA012171LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	hIST1 antibody; Increased sodium tolerance 1 antibody; Increased sodium tolerance 1 homolog antibody; IST1 homolog antibody; IST1_HUMAN antibody; KIAA0174 antibody; MAPK activating protein PM28 antibody; MGC117220 antibody; MGC128433 antibody; Putative MAPK-activating protein PM28 antibody
Similar products	IST1, KIAA0174, IST1 homolog (hIST1) (Putative MAPK-activating protein PM28)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	IST1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	hIST1 antibody; Increased sodium tolerance 1 antibody; Increased sodium tolerance 1 homolog antibody; IST1 homolog antibody; IST1_HUMAN antibody; KIAA0174 antibody; MAPK activating protein PM28 antibody; MGC117220 antibody; MGC128433 antibody; Putative MAPK-activating protein PM28 antibody
Immunogen Species	Human
Immunogen	Recombinant Human IST1 homolog protein (172-284AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:200-1:500 IF:1:50-1:200
Background	ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed:19129479, PubMed:19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (PubMed:26040712). Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed:23897888).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human IST1 homolog protein (172-284AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 25.09.2025

Express-Lieferung: 6 Tage sparen

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