REST Antibody

ArtNr	CSB-PA019571LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Neuroscience Neural Development Antibodies ELISA Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Neural Restrictive Silencer Factor antibody; Neural-restrictive silencer factor antibody; Neuron Restrictive Silencer Factor antibody; NRSF antibody; RE1 silencing transcription factor antibody; RE1-silencing transcription factor antibody; Repressor binding to the X2 box antibody; rest antibody; REST protein antibody; REST_HUMAN antibody; X2 box repressor antibody; XBR antibody
Similar products	REST, RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor), NRSF XBR
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	REST
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Neural Restrictive Silencer Factor antibody; Neural-restrictive silencer factor antibody; Neuron Restrictive Silencer Factor antibody; NRSF antibody; RE1 silencing transcription factor antibody; RE1-silencing transcription factor antibody; Repressor binding to the X2 box antibody; rest antibody; REST protein antibody; REST_HUMAN antibody; X2 box repressor antibody; XBR antibody
Immunogen Species	Human
Immunogen	Recombinant Human RE1-silencing transcription factor protein (250-350AA)
Dilution	ELISA:1:2000-1:10000 IF:1:50-1:200
Background	Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human RE1-silencing transcription factor protein (250-350AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 2 Tage sparen

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