SOCS3 Antibody

ArtNr	CSB-PA022392EA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Obesity Immunohistochemistry ELISA Immunofluorescence Enzymes Fatty Acid Synthesis Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ATOD4 antibody; CIS 3 antibody; CIS-3 antibody; CIS3 antibody; Cish3 antibody; Cytokine induced SH2 protein 3 antibody; Cytokine-inducible SH2 protein 3 antibody; E2a Pbx1 target gene in fibroblasts 10 antibody; EF 10 antibody; MGC71791 antibody; SOCS 3 antibody; SOCS-3 antibody; Socs3 antibody; SOCS3_HUMAN antibody; SSI 3 antibody; SSI-3 antibody; SSI3 antibody; STAT induced STAT inhibitor 3 antibody; STAT-induced STAT inhibitor 3 antibody; Suppressor of cytokine signaling 3 antibody
Similar products	SOCS3, Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3), CIS3 SSI3
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	SOCS3
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	ATOD4 antibody; CIS 3 antibody; CIS-3 antibody; CIS3 antibody; Cish3 antibody; Cytokine induced SH2 protein 3 antibody; Cytokine-inducible SH2 protein 3 antibody; E2a Pbx1 target gene in fibroblasts 10 antibody; EF 10 antibody; MGC71791 antibody; SOCS 3 antibody; SOCS-3 antibody; Socs3 antibody; SOCS3_HUMAN antibody; SSI 3 antibody; SSI-3 antibody; SSI3 antibody; STAT induced STAT inhibitor 3 antibody; STAT-induced STAT inhibitor 3 antibody; Suppressor of cytokine signaling 3 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Suppressor of cytokine signaling 3 protein (1-224AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:200
Background	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Immunology
Initial Research Areas	Immunology
Antigen Species	Human
Antigen	Recombinant Human Suppressor of cytokine signaling 3 protein (1-224AA)
Clonality	Polyclonal

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Menge: 50 ug

lieferbar

Lieferung vsl. bis 02.10.2025