TRIAP1 Antibody

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Recombinant Human TP53-regulated inhibitor of apoptosis 1 protein (1-76AA)

Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo) (PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (PubMed:15735003).

Antigen Affinity Purified

Human

Polyclonal